Takaisin Tulosta

Skitosofrenia, näytönastekatsausten kirjallisuusviitteet

Lisätietoa aiheesta
Käypä hoito -toimitus

Kirjallisuusviiteluettelosta löytyy koottuna Käypä hoito -suosituksen Skitsofrenia «Skitsofrenia»1 näytönastekatsauksissa arvioitu kirjallisuus.


  1. Addington J, Epstein I, Liu L ym. A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosis. Schizophr Res 2011;125:54-61 «PMID: 21074974»PubMed
  2. Amminger GP, Schäfer MR, Papageorgiou K ym. Long-chain omega-3 fatty acids for indicated prevention of psychotic disorders: a randomized, placebo-controlled trial. Arch Gen Psychiatry 2010;67:146-54 «PMID: 20124114»PubMed
  3. Babalola O, Gormez V, Alwan NA ym. Length of hospitalisation for people with severe mental illness. Cochrane Database Syst Rev 2014;:CD000384 «PMID: 24477710»PubMed
  4. Barkhof E, Meijer CJ, de Sonneville LM ym. Interventions to improve adherence to antipsychotic medication in patients with schizophrenia--a review of the past decade. Eur Psychiatry 2012;27:9-18 «PMID: 21561742»PubMed
  5. Bechdolf A, Wagner M, Ruhrmann S ym. Preventing progression to first-episode psychosis in early initial prodromal states. Br J Psychiatry 2012;200:22-9 «PMID: 22075649»PubMed
  6. Bell MD, Bryson GJ, Greig TC ym. Neurocognitive enhancement therapy with work therapy: Productivity outcomes at 6- and 12-month follow-ups. J Rehabil Res Dev 2005;42:829-38 «PMID: 16680620»PubMed
  7. Bell MD, Choi KH, Dyer C ym. Benefits of cognitive remediation and supported employment for schizophrenia patients with poor community functioning. Psychiatr Serv 2014;65:469-75 «PMID: 24382594»PubMed
  8. Bergman H. Social skills programmes for schizophrenia. Cochrane Database Syst Rev 2015;(6):1465-858
  9. Bordon N, O'Rourke S, Hutton P. The feasibility and clinical benefits of improving facial affect recognition impairments in schizophrenia: Systematic review and meta-analysis. Schizophr Res 2017;188:3-12 «PMID: 28095998»PubMed
  10. Bowie CR, McGurk SR, Mausbach B ym. Combined cognitive remediation and functional skills training for schizophrenia: effects on cognition, functional competence, and real-world behavior. Am J Psychiatry 2012;169:710-8 «PMID: 22581070»PubMed
  11. Bowtell M, Ratheesh A, McGorry P ym. Clinical and demographic predictors of continuing remission or relapse following discontinuation of antipsychotic medication after a first episode of psychosis. A systematic review. Schizophr Res 2018;197:9-18 «PMID: 29146020»PubMed
  12. Buckley LA, Maayan N, Soares-Weiser K ym. Supportive therapy for schizophrenia. Cochrane Database Syst Rev 2015;:CD004716 «PMID: 25871462»PubMed
  13. Burns T, Catty J, Becker T ym. The effectiveness of supported employment for people with severe mental illness: a randomised controlled trial. Lancet 2007;370:1146-52 «PMID: 17905167»PubMed
  14. Caemmerer J, Correll CU, Maayan L. Acute and maintenance effects of non-pharmacologic interventions for antipsychotic associated weight gain and metabolic abnormalities: a meta-analytic comparison of randomized controlled trials. Schizophr Res 2012;140:159-68 «PMID: 22763424»PubMed
  15. Castelein S, Bruggeman R, van Busschbach JT ym. The effectiveness of peer support groups in psychosis: a randomized controlled trial. Acta Psychiatr Scand 2008;118:64-72 «PMID: 18595176»PubMed
  16. Cella M, Preti A, Edwards C ym. Cognitive remediation for negative symptoms of schizophrenia: A network meta-analysis. Clin Psychol Rev 2017;52:43-51 «PMID: 27930934»PubMed
  17. Chadwick P, Strauss C, Jones AM ym. Group mindfulness-based intervention for distressing voices: A pragmatic randomised controlled trial. Schizophr Res 2016;175:168-173 «PMID: 27146475»PubMed
  18. Chakos M, Lieberman J, Hoffman E ym. Effectiveness of second-generation antipsychotics in patients with treatment-resistant schizophrenia: a review and meta-analysis of randomized trials. Am J Psychiatry 2001;158:518-26 «PMID: 11282684»PubMed
  19. Chan JY, Hirai HW, Tsoi KK. Can computer-assisted cognitive remediation improve employment and productivity outcomes of patients with severe mental illness? A meta-analysis of prospective controlled trials. J Psychiatr Res 2015;68:293-300 «PMID: 26028551»PubMed
  20. Chien WT, Bressington D, Yip A ym. An international multi-site, randomized controlled trial of a mindfulness-based psychoeducation group programme for people with schizophrenia. Psychol Med 2017;47:2081-2096 «PMID: 28374661»PubMed
  21. Chung J, Woods-Giscombe C. Influence of Dosage and Type of Music Therapy in Symptom Management and Rehabilitation for Individuals with Schizophrenia. Issues Ment Health Nurs 2016;37:631-641 «PMID: 27192343»PubMed
  22. Claus A, Bollen J, De Cuyper H ym. Risperidone versus haloperidol in the treatment of chronic schizophrenic inpatients: a multicentre double-blind comparative study. Acta Psychiatr Scand 1992;85:295-305 «PMID: 1375801»PubMed
  23. Cook JA, Blyler CR, McFarlane WR ym. Effectiveness of supported employment for individuals with schizophrenia: results of a multi-site randomized trial. Clin Schizophr Relat Psych 2008;2:37-46
  24. Crawford MJ, Killaspy H, Barnes TR ym. Group art therapy as an adjunctive treatment for people with schizophrenia: multicentre pragmatic randomised trial. BMJ 2012;344:e846 «PMID: 22374932»PubMed
  25. de Silva VA, Suraweera C, Ratnatunga SS ym. Metformin in prevention and treatment of antipsychotic induced weight gain: a systematic review and meta-analysis. BMC Psychiatry 2016;16:341 «PMID: 27716110»PubMed
  26. Dekker J, Wijdenes W, Koning YA ym. Assertive community treatment in Amsterdam. Community Ment Health J 2002;38:425-34 «PMID: 12236412»PubMed
  27. Dold M, Li C, Tardy M ym. Benzodiazepines for schizophrenia. Cochrane Database Syst Rev 2012;11:CD006391 «PMID: 23152236»PubMed
  28. Eack SM, Hogarty GE, Greenwald DP ym. Effects of Cognitive Enhancement Therapy on Employment Outcomes in Early Schizophrenia: Results From a Two-Year Randomized Trial. Res Soc Work Pract 2011;21:32-42 «PMID: 23885163»PubMed
  29. Eack SM, Keshavan M. Integrating the treatment of social and non-social cognitive impairments in schizophrenia with cognitive enhancement therapy. Schizophrenia Bullet 2013;39:S328
  30. Eichner C, Berna F. Acceptance and Efficacy of Metacognitive Training (MCT) on Positive Symptoms and Delusions in Patients With Schizophrenia: A Meta-analysis Taking Into Account Important Moderators. Schizophr Bull 2016;42:952-62 «PMID: 26748396»PubMed
  31. Firth J, Cotter J, Elliott R ym. A systematic review and meta-analysis of exercise interventions in schizophrenia patients. Psychol Med 2015;45:1343-61 «PMID: 25650668»PubMed
  32. Fredrick MM, Mintz J, Roberts DL ym. Is cognitive adaptation training (CAT) compensatory, restorative, or both? Schizophr Res 2015;166:290-6 «PMID: 26126419»PubMed
  33. Fusar-Poli P, Papanastasiou E, Stahl D ym. Treatments of Negative Symptoms in Schizophrenia: Meta-Analysis of 168 Randomized Placebo-Controlled Trials. Schizophr Bull 2015;41:892-9 «PMID: 25528757»PubMed
  34. Galling B, Roldán A, Hagi K ym. Antipsychotic augmentation vs. monotherapy in schizophrenia: systematic review, meta-analysis and meta-regression analysis. World Psychiatry 2017;16:77-89 «PMID: 28127934»PubMed
  35. Galling B, Vernon JA, Pagsberg AK ym. Efficacy and safety of antidepressant augmentation of continued antipsychotic treatment in patients with schizophrenia. Acta Psychiatr Scand 2018;137:187-205 «PMID: 29431197»PubMed
  36. Geretsegger M, Mössler KA, Bieleninik L ym. Music therapy for people with schizophrenia and schizophrenia-like disorders. Cochrane Database Syst Rev 2017;5:CD004025 «PMID: 28553702»PubMed
  37. Gillies D, Beck A, McCloud A ym. Benzodiazepines alone or in combination with antipsychotic drugs for acute psychosis. Cochrane Database Syst Rev 2005;:CD003079 «PMID: 16235313»PubMed
  38. Girón M, Fernández-Yañez A, Mañá-Alvarenga S ym. Efficacy and effectiveness of individual family intervention on social and clinical functioning and family burden in severe schizophrenia: a 2-year randomized controlled study. Psychol Med 2010;40:73-84 «PMID: 19490746»PubMed
  39. Goulet K, Deschamps B, Evoy F ym. Use of brain imaging (computed tomography and magnetic resonance imaging) in first-episode psychosis: review and retrospective study. Can J Psychiatry 2009;54:493-501 «PMID: 19660172»PubMed
  40. Grant N, Lawrence M, Preti A ym. Social cognition interventions for people with schizophrenia: a systematic review focussing on methodological quality and intervention modality. Clin Psychol Rev 2017;56:55-64 «PMID: 28688282»PubMed
  41. Grant PM, Bredemeier K, Beck AT. Six-Month Follow-Up of Recovery-Oriented Cognitive Therapy for Low-Functioning Individuals With Schizophrenia. Psychiatr Serv 2017;68:997-1002 «PMID: 28566022»PubMed
  42. Grant PM, Huh GA, Perivoliotis D ym. Randomized trial to evaluate the efficacy of cognitive therapy for low-functioning patients with schizophrenia. Arch Gen Psychiatry 2012;69:121-7 «PMID: 21969420»PubMed
  43. Grawe RW, Falloon IR, Widen JH ym. Two years of continued early treatment for recent-onset schizophrenia: a randomised controlled study. Acta Psychiatr Scand 2006;114:328-36 «PMID: 17022792»PubMed
  44. Gregory A, Mallikarjun P, Upthegrove R. Treatment of depression in schizophrenia: systematic review and meta-analysis. Br J Psychiatry 2017;211:198-204 «PMID: 28882827»PubMed
  45. Haukka J, Tiihonen J, Härkänen T ym. Association between medication and risk of suicide, attempted suicide and death in nationwide cohort of suicidal patients with schizophrenia. Pharmacoepidemiol Drug Saf 2008;17:686-96 «PMID: 18327869»PubMed
  46. He H, Lu J, Yang L ym. Repetitive transcranial magnetic stimulation for treating the symptoms of schizophrenia: A PRISMA compliant meta-analysis. Clin Neurophysiol 2017;128:716-724 «PMID: 28315614»PubMed
  47. Helfer B, Samara MT, Huhn M ym. Efficacy and Safety of Antidepressants Added to Antipsychotics for Schizophrenia: A Systematic Review and Meta-Analysis. Am J Psychiatry 2016;173:876-86 «PMID: 27282362»PubMed
  48. Hennen J, Baldessarini RJ. Suicidal risk during treatment with clozapine: a meta-analysis. Schizophr Res 2005;73:139-45 «PMID: 15653256»PubMed
  49. Hudson TJ, Owen RR, Thrush CR ym. Guideline implementation and patient-tailoring strategies to improve medication adherence for schizophrenia. J Clin Psychiatry 2008;69:74-80 «PMID: 18312040»PubMed
  50. Huhn M, Nikolakopoulou A, Schneider-Thoma J ym. Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis. Lancet 2019;394:939-951 «PMID: 31303314»PubMed
  51. Huttunen MO, Piepponen T, Rantanen H ym. Risperidone versus zuclopenthixol in the treatment of acute schizophrenic episodes: a double-blind parallel-group trial. Acta Psychiatr Scand 1995;91:271-7 «PMID: 7542829»PubMed
  52. Ising HK, Kraan TC, Rietdijk J ym. Four-Year Follow-up of Cognitive Behavioral Therapy in Persons at Ultra-High Risk for Developing Psychosis: The Dutch Early Detection Intervention Evaluation (EDIE-NL) Trial. Schizophr Bull 2016;42:1243-52 «PMID: 26994397»PubMed
  53. Ising HK, Lokkerbol J, Rietdijk J ym. Four-Year Cost-effectiveness of Cognitive Behavior Therapy for Preventing First-episode Psychosis: The Dutch Early Detection Intervention Evaluation (EDIE-NL) Trial. Schizophr Bull 2017;43:365-374 «PMID: 27306315»PubMed
  54. Joffe G, Terevnikov V, Joffe M ym. Add-on mirtazapine enhances antipsychotic effect of first generation antipsychotics in schizophrenia: a double-blind, randomized, placebo-controlled trial. Schizophr Res 2009;108:245-51 «PMID: 19144501»PubMed
  55. Jones C, Hacker D, Xia J ym. Cognitive behavioural therapy plus standard care versus standard care for people with schizophrenia. Cochrane Database Syst Rev 2018;12:CD007964 «PMID: 30572373»PubMed
  56. Joy CB, Adams CE, Rice K. Crisis intervention for people with severe mental illnesses. Cochrane Database Syst Rev 2006;:CD001087 «PMID: 17054133»PubMed
  57. Kane JM, Robinson DG, Schooler NR ym. Comprehensive Versus Usual Community Care for First-Episode Psychosis: 2-Year Outcomes From the NIMH RAISE Early Treatment Program. Am J Psychiatry 2016;173:362-72 «PMID: 26481174»PubMed
  58. Khandanpour N, Hoggard N, Connolly DJ. The role of MRI and CT of the brain in first episodes of psychosis. Clin Radiol 2013;68:245-50 «PMID: 22959259»PubMed
  59. Killaspy H, Bebbington P, Blizard R ym. The REACT study: randomised evaluation of assertive community treatment in north London. BMJ 2006;332:815-20 «PMID: 16543298»PubMed
  60. Kinoshita Y, Furukawa TA, Kinoshita K ym. Supported employment for adults with severe mental illness. Cochrane Database Syst Rev 2013;:CD008297 «PMID: 24030739»PubMed
  61. Kirli S, Caliskan M. A comparative study of sertraline versus imipramine in postpsychotic depressive disorder of schizophrenia. Schizophr Res 1998;33:103-11 «PMID: 9783350»PubMed
  62. Kishimoto T, Robenzadeh A, Leucht C ym. Long-acting injectable vs oral antipsychotics for relapse prevention in schizophrenia: a meta-analysis of randomized trials. Schizophr Bull 2014;40:192-213 «PMID: 23256986»PubMed
  63. Krause M, Zhu Y, Huhn M ym. Antipsychotic drugs for patients with schizophrenia and predominant or prominent negative symptoms: a systematic review and meta-analysis. Eur Arch Psychiatry Clin Neurosci 2018;268:625-639 «PMID: 29368205»PubMed
  64. Kurtz MM, Mueser KT. A meta-analysis of controlled research on social skills training for schizophrenia. J Consult Clin Psychol 2008;76:491-504 «PMID: 18540742»PubMed
  65. Lasser RA, Bossie CA, Gharabawi GM ym. Remission in schizophrenia: Results from a 1-year study of long-acting risperidone injection. Schizophr Res 2005;77:215-27 «PMID: 15908183»PubMed
  66. Lauriello J, Lambert T, Andersen S ym. An 8-week, double-blind, randomized, placebo-controlled study of olanzapine long-acting injection in acutely ill patients with schizophrenia. J Clin Psychiatry 2008;69:790-9 «PMID: 18452346»PubMed
  67. Leucht S, Barnes TR, Kissling W ym. Relapse prevention in schizophrenia with new-generation antipsychotics: a systematic review and exploratory meta-analysis of randomized, controlled trials. Am J Psychiatry 2003;160:1209-22 «PMID: 12832232»PubMed
  68. Leucht S, Cipriani A, Spineli L ym. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Lancet 2013;382:951-62 «PMID: 23810019»PubMed
  69. Leucht S, Corves C, Arbter D ym. Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet 2009;373:31-41 «PMID: 19058842»PubMed
  70. Leucht S, Komossa K, Rummel-Kluge C ym. A meta-analysis of head-to-head comparisons of second-generation antipsychotics in the treatment of schizophrenia. Am J Psychiatry 2009;166:152-63 «PMID: 19015230»PubMed
  71. Leucht S, Leucht C, Huhn M ym. Sixty Years of Placebo-Controlled Antipsychotic Drug Trials in Acute Schizophrenia: Systematic Review, Bayesian Meta-Analysis, and Meta-Regression of Efficacy Predictors. Am J Psychiatry 2017;174:927-942 «PMID: 28541090»PubMed
  72. Lewis SW, Davies L, Jones PB ym. Randomised controlled trials of conventional antipsychotic versus new atypical drugs, and new atypical drugs versus clozapine, in people with schizophrenia responding poorly to, or intolerant of, current drug treatment. Health Technol Assess 2006;10:iii-iv, ix-xi, 1-165 «PMID: 16707074»PubMed
  73. Li ZJ, Guo ZH, Wang N ym. Cognitive-behavioural therapy for patients with schizophrenia: a multicentre randomized controlled trial in Beijing, China. Psychol Med 2015;45:1893-905 «PMID: 25532460»PubMed
  74. Lieberman JA, Stroup TS, McEvoy JP ym. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med 2005;353:1209-23 «PMID: 16172203»PubMed
  75. Lindenmayer JP, Khan A, McGurk SR ym. Does social cognition training augment response to computer-assisted cognitive remediation for schizophrenia? Schizophr Res 2018;201:180-186 «PMID: 29910120»PubMed
  76. Liu YC, Tang CC, Hung TT ym. The Efficacy of Metacognitive Training for Delusions in Patients With Schizophrenia: A Meta-Analysis of Randomized Controlled Trials Informs Evidence-Based Practice. Worldviews Evid Based Nurs 2018;15:130-139 «PMID: 29489070»PubMed
  77. Lubman DI, Velakoulis D, McGorry PD ym. Incidental radiological findings on brain magnetic resonance imaging in first-episode psychosis and chronic schizophrenia. Acta Psychiatr Scand 2002;106:331-6 «PMID: 12366466»PubMed
  78. Lynch D, Laws KR, McKenna PJ. Cognitive behavioural therapy for major psychiatric disorder: does it really work? A meta-analytical review of well-controlled trials. Psychol Med 2010;40:9-24 «PMID: 19476688»PubMed
  79. Lystad JU, Falkum E, Haaland VØ ym. Cognitive remediation and occupational outcome in schizophrenia spectrum disorders: A 2year follow-up study. Schizophr Res 2017;185:122-129 «PMID: 28041917»PubMed
  80. Malchow B, Keller K, Hasan A ym. Effects of Endurance Training Combined With Cognitive Remediation on Everyday Functioning, Symptoms, and Cognition in Multiepisode Schizophrenia Patients. Schizophr Bull 2015;41:847-58 «PMID: 25782770»PubMed
  81. Malmberg L, Fenton M. Individual psychodynamic psychotherapy and psychoanalysis for schizophrenia and severe mental illness. Cochrane Database Syst Rev 2001;:CD001360 «PMID: 11686988»PubMed
  82. Malone D, Newron-Howes G, Simmonds S ym. Community mental health teams (CMHTs) for people with severe mental illnesses and disordered personality. Cochrane Database Syst Rev 2007;:CD000270 «PMID: 17636625»PubMed
  83. Marder SR, Davis JM, Chouinard G. The effects of risperidone on the five dimensions of schizophrenia derived by factor analysis: combined results of the North American trials. J Clin Psychiatry 1997;58:538-46 «PMID: 9448657»PubMed
  84. Marshall M, Lockwood A. WITHDRAWN: Assertive community treatment for people with severe mental disorders. Cochrane Database Syst Rev 2011;:CD001089 «PMID: 21491382»PubMed
  85. Martin JL, Pérez V, Sacristán M ym. Meta-analysis of drop-out rates in randomised clinical trials, comparing typical and atypical antipsychotics in the treatment of schizophrenia. Eur Psychiatry 2006;21:11-20 «PMID: 16380237»PubMed
  86. Mayoral F, Berrozpe A, de la Higuera J ym. Efficacy of a family intervention program for prevention of hospitalization in patients with schizophrenia. A naturalistic multicenter controlled and randomized study in Spain. Rev Psiquiatr Salud Ment 2015;8:83-91 «PMID: 25017624»PubMed
  87. McEvoy JP, Lieberman JA, Stroup TS ym. Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment. Am J Psychiatry 2006;163:600-10 «PMID: 16585434»PubMed
  88. McGlashan TH, Zipursky RB, Perkins D ym. Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis. Am J Psychiatry 2006;163:790-9 «PMID: 16648318»PubMed
  89. McGorry PD, Nelson B, Phillips LJ ym. Randomized controlled trial of interventions for young people at ultra-high risk of psychosis: twelve-month outcome. J Clin Psychiatry 2013;74:349-56 «PMID: 23218022»PubMed
  90. McGorry PD, Yung AR, Phillips LJ ym. Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms. Arch Gen Psychiatry 2002;59:921-8 «PMID: 12365879»PubMed
  91. Meltzer HY, Alphs L, Green AI ym. Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT). Arch Gen Psychiatry 2003;60:82-91 «PMID: 12511175»PubMed
  92. Miklowitz DJ, O'Brien MP, Schlosser DA ym. Family-focused treatment for adolescents and young adults at high risk for psychosis: results of a randomized trial. J Am Acad Child Adolesc Psychiatry 2014;53:848-58 «PMID: 25062592»PubMed
  93. Modini M, Tan L, Brinchmann B ym. Supported employment for people with severe mental illness: systematic review and meta-analysis of the international evidence. Br J Psychiatry 2016;209:14-22 «PMID: 27103678»PubMed
  94. Moilanen J, Haapea M, Miettunen J ym. Characteristics of subjects with schizophrenia spectrum disorder with and without antipsychotic medication - a 10-year follow-up of the Northern Finland 1966 Birth Cohort study. Eur Psychiatry 2013;28:53-8 «PMID: 21920710»PubMed
  95. Montes JM, Maurino J, Diez T ym. Telephone-based nursing strategy to improve adherence to antipsychotic treatment in schizophrenia: A controlled trial. Int J Psychiatry Clin Pract 2010;14:274-81 «PMID: 24917439»PubMed
  96. Moriana JA, Alarcón E, Herruzo J. In-home psychosocial skills training for patients with schizophrenia. Psychiatr Serv 2006;57:260-2 «PMID: 16452707»PubMed
  97. Moritz S, Veckenstedt R, Andreou C ym. Sustained and "sleeper" effects of group metacognitive training for schizophrenia: a randomized clinical trial. JAMA Psychiatry 2014;71:1103-11 «PMID: 25103718»PubMed
  98. Morrison AP, French P, Parker S ym. Three-year follow-up of a randomized controlled trial of cognitive therapy for the prevention of psychosis in people at ultrahigh risk. Schizophr Bull 2007;33:682-7 «PMID: 16973786»PubMed
  99. Morrison AP, French P, Stewart SL ym. Early detection and intervention evaluation for people at risk of psychosis: multisite randomised controlled trial. BMJ 2012;344:e2233 «PMID: 22491790»PubMed
  100. Morrison AP, French P, Walford L ym. Cognitive therapy for the prevention of psychosis in people at ultra-high risk: randomised controlled trial. Br J Psychiatry 2004;185:291-7 «PMID: 15458988»PubMed
  101. Morrison AP, Hutton P, Wardle M ym. Cognitive therapy for people with a schizophrenia spectrum diagnosis not taking antipsychotic medication: an exploratory trial. Psychol Med 2012;42:1049-56 «PMID: 21914252»PubMed
  102. Morrison AP, Turkington D, Pyle M ym. Cognitive therapy for people with schizophrenia spectrum disorders not taking antipsychotic drugs: a single-blind randomised controlled trial. Lancet 2014;383:1395-403 «PMID: 24508320»PubMed
  103. Morriss R, Vinjamuri I, Faizal MA ym. Training to recognize the early signs of recurrence in schizophrenia. Schizophr Bull 2013;39:255-6 «PMID: 23325785»PubMed
  104. Murphy BP, Chung YC, Park TW ym. Pharmacological treatment of primary negative symptoms in schizophrenia: a systematic review. Schizophr Res 2006;88:5-25 «PMID: 16930948»PubMed
  105. Mössler K, Chen X, Heldal TO ym. Music therapy for people with schizophrenia and schizophrenia-like disorders. Cochrane Database Syst Rev 2011;:CD004025 «PMID: 22161383»PubMed
  106. Naeem F, Khoury B, Munshi T ym. Brief cognitive behavioral therapy for psychosis (CBTp) for schizophrenia: Literature review and meta-analysis. Int J Cogn Ther 2016;9:73-86
  107. Naslund JA, Whiteman KL, McHugo GJ ym. Lifestyle interventions for weight loss among overweight and obese adults with serious mental illness: A systematic review and meta-analysis. Gen Hosp Psychiatry 2017;47:83-102 «PMID: 28807143»PubMed
  108. Nelson B, Amminger GP, Yuen HP ym. NEURAPRO: a multi-centre RCT of omega-3 polyunsaturated fatty acids versus placebo in young people at ultra-high risk of psychotic disorders-medium-term follow-up and clinical course. NPJ Schizophr 2018;4:11 «PMID: 29941938»PubMed
  109. Nordentoft M, Øhlenschlaeger J, Thorup A ym. Deinstitutionalization revisited: a 5-year follow-up of a randomized clinical trial of hospital-based rehabilitation versus specialized assertive intervention (OPUS) versus standard treatment for patients with first-episode schizophrenia spectrum disorders. Psychol Med 2010;40:1619-26 «PMID: 20059798»PubMed
  110. Nuechterlein KH, Ventura J, McEwen SC ym. Enhancing Cognitive Training Through Aerobic Exercise After a First Schizophrenia Episode: Theoretical Conception and Pilot Study. Schizophr Bull 2016;42 Suppl 1:S44-52 «PMID: 27460618»PubMed
  111. O'Brien MP, Miklowitz DJ, Candan KA ym. A randomized trial of family focused therapy with populations at clinical high risk for psychosis: effects on interactional behavior. J Consult Clin Psychol 2014;82:90-101 «PMID: 24188511»PubMed
  112. Ochoa S, López-Carrilero R, Barrigón ML ym. Randomized control trial to assess the efficacy of metacognitive training compared with a psycho-educational group in people with a recent-onset psychosis. Psychol Med 2017;47:1573-1584 «PMID: 28166848»PubMed
  113. Peña J, Ibarretxe-Bilbao N, Sánchez P ym. Combining social cognitive treatment, cognitive remediation, and functional skills training in schizophrenia: a randomized controlled trial. NPJ Schizophr 2016;2:16037 «PMID: 27868083»PubMed
  114. Petersen L, Jeppesen P, Thorup A ym. A randomised multicentre trial of integrated versus standard treatment for patients with a first episode of psychotic illness. BMJ 2005;331:602 «PMID: 16141449»PubMed
  115. Petrides G, Malur C, Braga RJ ym. Electroconvulsive therapy augmentation in clozapine-resistant schizophrenia: a prospective, randomized study. Am J Psychiatry 2015;172:52-8 «PMID: 25157964»PubMed
  116. Pfammatter M, Junghan UM, Brenner HD. Efficacy of psychological therapy in schizophrenia: conclusions from meta-analyses. Schizophr Bull 2006;32 Suppl 1:S64-80 «PMID: 16905634»PubMed
  117. Pharoah F, Mari J, Rathbone J ym. Family intervention for schizophrenia. Cochrane Database Syst Rev 2010;:CD000088 «PMID: 21154340»PubMed
  118. Phillips LJ, McGorry PD, Yuen HP ym. Medium term follow-up of a randomized controlled trial of interventions for young people at ultra high risk of psychosis. Schizophr Res 2007;96:25-33 «PMID: 17611080»PubMed
  119. Pilling S, Bebbington P, Kuipers E ym. Psychological treatments in schizophrenia: II. Meta-analyses of randomized controlled trials of social skills training and cognitive remediation. Psychol Med 2002;32:783-91 «PMID: 12171373»PubMed
  120. Pirkola S, Sohlman B, Heilä H ym. Reductions in postdischarge suicide after deinstitutionalization and decentralization: a nationwide register study in Finland. Psychiatr Serv 2007;58:221-6 «PMID: 17287379»PubMed
  121. Pitschel-Walz G, Bäuml J, Bender W ym. Psychoeducation and compliance in the treatment of schizophrenia: results of the Munich Psychosis Information Project Study. J Clin Psychiatry 2006;67:443-52 «PMID: 16649832»PubMed
  122. Ran M, Xiang M, Huang M ym. Natural course of schizophrenia: 2-year follow-up study in a rural Chinese community. Br J Psychiatry 2001;178:154-8 «PMID: 11157428»PubMed
  123. Robinson D, Woerner MG, Alvir JM ym. Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Arch Gen Psychiatry 1999;56:241-7 «PMID: 10078501»PubMed
  124. Rosenbaum B, Harder S, Knudsen P ym. Supportive psychodynamic psychotherapy versus treatment as usual for first-episode psychosis: two-year outcome. Psychiatry 2012;75:331-41 «PMID: 23244011»PubMed
  125. Rosenbaum B. Early and sustained dynamic intervention in schizophrenia. Psychiatr Danub 2009;21 Suppl 1:132-4 «PMID: 19789498»PubMed
  126. Rosenheck R, Mueser KT, Sint K ym. Supported employment and education in comprehensive, integrated care for first episode psychosis: Effects on work, school, and disability income. Schizophr Res 2017;182:120-128 «PMID: 27667369»PubMed
  127. Ruddy R, Milnes D. Art therapy for schizophrenia or schizophrenia-like illnesses. Cochrane Database Syst Rev 2005;:CD003728 «PMID: 16235338»PubMed
  128. Ruhrmann S, Bechdolf A, Kühn KU ym. Acute effects of treatment for prodromal symptoms for people putatively in a late initial prodromal state of psychosis. Br J Psychiatry Suppl 2007;51:s88-95 «PMID: 18055944»PubMed
  129. Sánchez P, Peña J, Bengoetxea E ym. Improvements in negative symptoms and functional outcome after a new generation cognitive remediation program: a randomized controlled trial. Schizophr Bull 2014;40:707-15 «PMID: 23686130»PubMed
  130. Sarin F, Wallin L, Widerlöv B. Cognitive behavior therapy for schizophrenia: a meta-analytical review of randomized controlled trials. Nord J Psychiatry 2011;65:162-74 «PMID: 21563994»PubMed
  131. Sin J, Gillard S, Spain D ym. Effectiveness of psychoeducational interventions for family carers of people with psychosis: A systematic review and meta-analysis. Clin Psychol Rev 2017;56:13-24 «PMID: 28578249»PubMed
  132. Sinclair DJ, Zhao S, Qi F ym. Electroconvulsive therapy for treatment-resistant schizophrenia. Cochrane Database Syst Rev 2019;3:CD011847 «PMID: 30888709»PubMed
  133. Singh SP, Singh V, Kar N ym. Efficacy of antidepressants in treating the negative symptoms of chronic schizophrenia: meta-analysis. Br J Psychiatry 2010;197:174-9 «PMID: 20807960»PubMed
  134. Siskind D, McCartney L, Goldschlager R ym. Clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis. Br J Psychiatry 2016;209:385-392 «PMID: 27388573»PubMed
  135. Sohlman B, Pirkola S, Wahlbeck K. Psykiatrisen sairaalahoidon lyhenemisen yhteys hoidonjälkeisiin itsemurhiin. Duodecim 2006;122:819-25
  136. Sommer IE, de Kort GA, Meijering AL ym. How frequent are radiological abnormalities in patients with psychosis? A review of 1379 MRI scans. Schizophr Bull 2013;39:815-9 «PMID: 22416264»PubMed
  137. Strahl B, Cheung YK, Stuckey SL. Diagnostic yield of computed tomography of the brain in first episode psychosis. J Med Imaging Radiat Oncol 2010;54:431-4 «PMID: 20958941»PubMed
  138. Stubbs B, Vancampfort D, Hallgren M ym. EPA guidance on physical activity as a treatment for severe mental illness: a meta-review of the evidence and Position Statement from the European Psychiatric Association (EPA), supported by the International Organization of Physical Therapists in Mental Health (IOPTMH). Eur Psychiatry 2018;54:124-144 «PMID: 30257806»PubMed
  139. Sytema S, Wunderink L, Bloemers W ym. Assertive community treatment in the Netherlands: a randomized controlled trial. Acta Psychiatr Scand 2007;116:105-12 «PMID: 17650271»PubMed
  140. Tarrier N. Cognitive behavior therapy for schizophrenia and psychosis: current status and future directions. Clin Schizophr Relat Psychoses 2010;4:176-84 «PMID: 20880828»PubMed
  141. Tas C, Danaci AE, Cubukcuoglu Z ym. Impact of family involvement on social cognition training in clinically stable outpatients with schizophrenia -- a randomized pilot study. Psychiatry Res 2012;195:32-8 «PMID: 21831453»PubMed
  142. Terevnikov V, Stenberg JH, Tiihonen J ym. Add-on mirtazapine improves depressive symptoms in schizophrenia: a double-blind randomized placebo-controlled study with an open-label extension phase. Hum Psychopharmacol 2011;26:188-93 «PMID: 21469215»PubMed
  143. Tiihonen J, Haukka J, Taylor M ym. A nationwide cohort study of oral and depot antipsychotics after first hospitalization for schizophrenia. Am J Psychiatry 2011;168:603-9 «PMID: 21362741»PubMed
  144. Tiihonen J, Mittendorfer-Rutz E, Majak M ym. Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29?823 Patients With Schizophrenia. JAMA Psychiatry 2017;74:686-693 «PMID: 28593216»PubMed
  145. Tiihonen J, Suokas JT, Suvisaari JM ym. Polypharmacy with antipsychotics, antidepressants, or benzodiazepines and mortality in schizophrenia. Arch Gen Psychiatry 2012;69:476-83 «PMID: 22566579»PubMed
  146. Tiihonen J, Taipale H, Mehtälä J ym. Association of Antipsychotic Polypharmacy vs Monotherapy With Psychiatric Rehospitalization Among Adults With Schizophrenia. JAMA Psychiatry 2019;76:499-507 «PMID: 30785608»PubMed
  147. Tiihonen J, Tanskanen A, Taipale H. 20-Year Nationwide Follow-Up Study on Discontinuation of Antipsychotic Treatment in First-Episode Schizophrenia. Am J Psychiatry 2018;175:765-773 «PMID: 29621900»PubMed
  148. Tiihonen J, Wahlbeck K, Kiviniemi V. The efficacy of lamotrigine in clozapine-resistant schizophrenia: a systematic review and meta-analysis. Schizophr Res 2009;109:10-4 «PMID: 19186030»PubMed
  149. Tiihonen J, Wahlbeck K, Lönnqvist J ym. Effectiveness of antipsychotic treatments in a nationwide cohort of patients in community care after first hospitalisation due to schizophrenia and schizoaffective disorder: observational follow-up study. BMJ 2006;333:224 «PMID: 16825203»PubMed
  150. Tollefson GD, Beasley CM Jr, Tran PV ym. Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial. Am J Psychiatry 1997;154:457-65 «PMID: 9090331»PubMed
  151. Tollefson GD, Sanger TM, Lu Y ym. Depressive signs and symptoms in schizophrenia: a prospective blinded trial of olanzapine and haloperidol. Arch Gen Psychiatry 1998;55:250-8 «PMID: 9510219»PubMed
  152. Tollefson GD, Sanger TM. Negative symptoms: a path analytic approach to a double-blind, placebo- and haloperidol-controlled clinical trial with olanzapine. Am J Psychiatry 1997;154:466-74 «PMID: 9090332»PubMed
  153. Tseng PT, Chen YW, Lin PY ym. Significant treatment effect of adjunct music therapy to standard treatment on the positive, negative, and mood symptoms of schizophrenic patients: a meta-analysis. BMC Psychiatry 2016;16:16 «PMID: 26812906»PubMed
  154. Tsujino N, Nemoto T, Morita K ym. Long-term Efficacy and Tolerability of Perospirone for Young Help-seeking People at Clinical High Risk: a Preliminary Open Trial. Clin Psychopharmacol Neurosci 2013;11:132-6 «PMID: 24465249»PubMed
  155. van der Gaag M, Nieman DH, Rietdijk J ym. Cognitive behavioral therapy for subjects at ultrahigh risk for developing psychosis: a randomized controlled clinical trial. Schizophr Bull 2012;38:1180-8 «PMID: 22941746»PubMed
  156. van der Gaag M, Valmaggia LR, Smit F. The effects of individually tailored formulation-based cognitive behavioural therapy in auditory hallucinations and delusions: a meta-analysis. Schizophr Res 2014;156:30-7 «PMID: 24731619»PubMed
  157. van Oosterhout B, Krabbendam L, de Boer K ym. Metacognitive group training for schizophrenia spectrum patients with delusions: a randomized controlled trial. Psychol Med 2014;44:3025-35 «PMID: 25066223»PubMed
  158. Vancampfort D, De Hert M, Knapen J ym. Effects of progressive muscle relaxation on state anxiety and subjective well-being in people with schizophrenia: a randomized controlled trial. Clin Rehabil 2011;25:567-75 «PMID: 21402653»PubMed
  159. Vancampfort D, Firth J, Correll CU ym. The impact of pharmacological and non-pharmacological interventions to improve physical health outcomes in people with schizophrenia: a meta-review of meta-analyses of randomized controlled trials. World Psychiatry 2019;18:53-66 «PMID: 30600626»PubMed
  160. Vancampfort D, Probst M, Helvik Skjaerven L ym. Systematic review of the benefits of physical therapy within a multidisciplinary care approach for people with schizophrenia. Phys Ther 2012;92:11-23 «PMID: 22052946»PubMed
  161. Wang LQ, Chien WT, Yip LK ym. A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up. Neuropsychiatr Dis Treat 2016;12:3097-3110 «PMID: 27994466»PubMed
  162. Velligan DI, Diamond PM, Maples NJ ym. Comparing the efficacy of interventions that use environmental supports to improve outcomes in patients with schizophrenia. Schizophr Res 2008;102:312-9 «PMID: 18374542»PubMed
  163. Velligan DI, Diamond PM, Mintz J ym. The use of individually tailored environmental supports to improve medication adherence and outcomes in schizophrenia. Schizophr Bull 2008;34:483-93 «PMID: 17932089»PubMed
  164. Velligan DI, Tai S, Roberts DL ym. A randomized controlled trial comparing cognitive behavior therapy, cognitive adaptation training, their combination and treatment as usual in chronic schizophrenia. Schizophr Bull 2015;41:597-603 «PMID: 25193976»PubMed
  165. Velthorst E, Koeter M, van der Gaag M ym. Adapted cognitive-behavioural therapy required for targeting negative symptoms in schizophrenia: meta-analysis and meta-regression. Psychol Med 2015;45:453-65 «PMID: 24993642»PubMed
  166. Ventura J, Subotnik KL, Gretchen-Doorly D ym. Cognitive remediation can improve negative symptoms and social functioning in first-episode schizophrenia: A randomized controlled trial. Schizophr Res 2019;203:24-31 «PMID: 29128326»PubMed
  167. Vera-Garcia E, Mayoral-Cleries F, Vancampfort D ym. A systematic review of the benefits of physical therapy within a multidisciplinary care approach for people with schizophrenia: An update. Psychiatry Res 2015;229:828-39 «PMID: 26254795»PubMed
  168. Vesterager L, Christensen T, Olsen B, Melau M, Krarup G, Nordentoft M. Cognitive remediation combined with a comprehensive psychosocial program for patients with first episode schizophrenia: the neuro com trial. Schizophrenia Bullet 2013;39:S356
  169. Winton-Brown TT, Elanjithara T, Power P ym. Five-fold increased risk of relapse following breaks in antipsychotic treatment of first episode psychosis. Schizophr Res 2017;179:50-56 «PMID: 27745754»PubMed
  170. Wood L, Byrne R, Varese F ym. Psychosocial interventions for internalised stigma in people with a schizophrenia-spectrum diagnosis: A systematic narrative synthesis and meta-analysis. Schizophr Res 2016;176:291-303 «PMID: 27256518»PubMed
  171. Woods SW, Tully EM, Walsh BC ym. Aripiprazole in the treatment of the psychosis prodrome: an open-label pilot study. Br J Psychiatry Suppl 2007;51:s96-101 «PMID: 18055946»PubMed
  172. Wunderink L, Nieboer RM, Wiersma D ym. Recovery in remitted first-episode psychosis at 7 years of follow-up of an early dose reduction/discontinuation or maintenance treatment strategy: long-term follow-up of a 2-year randomized clinical trial. JAMA Psychiatry 2013;70:913-20 «PMID: 23824214»PubMed
  173. Wykes T, Steel C, Everitt B ym. Cognitive behavior therapy for schizophrenia: effect sizes, clinical models, and methodological rigor. Schizophr Bull 2008;34:523-37 «PMID: 17962231»PubMed
  174. Zaman H, Gibson RC, Walcott G. Benzodiazepines for catatonia in people with schizophrenia or other serious mental illnesses. Cochrane Database Syst Rev 2019;8:CD006570 «PMID: 31425609»PubMed
  175. Zhao S, Sampson S, Xia J ym. Psychoeducation (brief) for people with serious mental illness. Cochrane Database Syst Rev 2015;:CD010823 «PMID: 25854522»PubMed
  176. Zheng W, Xiang YT, Yang XH ym. Clozapine Augmentation With Antiepileptic Drugs for Treatment-Resistant Schizophrenia: A Meta-Analysis of Randomized Controlled Trials. J Clin Psychiatry 2017;78:e498-e505 «PMID: 28355041»PubMed
  177. Ziguras SJ, Stuart GW. A meta-analysis of the effectiveness of mental health case management over 20 years. Psychiatr Serv 2000;51:1410-21 «PMID: 11058189»PubMed
  178. Zipursky RB, Menezes NM, Streiner DL. Risk of symptom recurrence with medication discontinuation in first-episode psychosis: a systematic review. Schizophr Res 2014;152:408-14 «PMID: 23972821»PubMed