Acute kidney injury (AKI) is associated with significant morbidity and mortality. Its prevalence is increasing. Risk factors are increased age, diabetes, atherosclerosis, medications, heart failure, male sex, and even mild chronic renal failure.

Early detection of AKI is essential, as is the prevention of AKI related to hypovolaemia, contrast agents and nephrotoxic medications. No medication is available for developed AKI, the only therapeutic option being renal replacement therapy. Thus, prevention by adequate fluid therapy, optimisation of renal perfusion pressure and exclusion of post-renal causes of AKI are crucial. To date, the long-term outcome in AKI is unsatisfactory and the costs are high.

A working group appointed by the Finnish Medical Society Duodecim, the Finnish Society of Ananesthesiologists, Subdivision of Intensive Care Medicine and the Finnish Society of Nephrology

Ville Pettilä (Chair)

Leena Halme

Merja Hanski

Eero Honkanen

Annika Laukkanen

Kaj Metsärinne

Seija Peltonen

Marja Puurunen (Current Care Editor)

Ari Uusaro

Maarit Wuorela