AIT includes the specific treatment of IgE-mediated allergic diseases, indicated for allergic rhinitis and conjunctivitis, allergic asthma, and venom allergy. Subcutaneous AIT with pollens, animal danders, insect venoms and house dust mite preparations for allergic rhinitis and asthma is effective and safe for adults and children. Sublingual AIT indicated for allergic rhinitis caused by grass pollens and birch is effective and safe. AIT may raise the threshold of reactivity to foods in children with severe food allergy but is associated with serious adverse effects and should be used only in clinical research settings.
Johannes Savolainen (Chair)