Unettomuus, näytönastekatsausten kirjallisuusviitteet
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Käypä hoito -toimitus
2.6.2026
Kirjallisuusviiteluettelosta löytyy koottuna Käypä hoito -suosituksen Unettomuus «Unettomuus»1 näytönastekatsauksissa arvioitu kirjallisuus.
Kirjallisuutta
- Abboud M. Vitamin D Supplementation and Sleep: A Systematic Review and Meta-Analysis
of Intervention Studies. Nutrients 2022;14(5): «PMID: 35268051»PubMed
- AlDawsari A, Bushell TJ, Abutheraa N, ym. Use of sedative-hypnotic medications and
risk of dementia: A systematic review and meta-analysis. Br J Clin Pharmacol 2022;88(4):1567-1589
«PMID: 34679196»PubMed
- Alessi CA, Fung CH, Dzierzewski JM, ym. Randomized controlled trial of an integrated
approach to treating insomnia and improving the use of positive airway pressure therapy
in veterans with comorbid insomnia disorder and obstructive sleep apnea. Sleep 2021;44(4):
«PMID: 33221910»PubMed
- Allain H, Bentué-Ferrer D, Tarral A, ym. Effects on postural oscillation and memory
functions of a single dose of zolpidem 5 mg, zopiclone 3.75 mg and lormetazepam 1
mg in elderly healthy subjects. A randomized, cross-over, double-blind study versus
placebo. Eur J Clin Pharmacol 2003;59(3):179-88 «PMID: 12756510»PubMed
- Ancoli-Israel S, Walsh JK, Mangano RM, ym. Zaleplon, A Novel Nonbenzodiazepine Hypnotic,
Effectively Treats Insomnia in Elderly Patients Without Causing Rebound Effects. Prim
Care Companion J Clin Psychiatry 1999;1(4):114-120 «PMID: 15014684»PubMed
- Anttila SA, Leinonen EV. A review of the pharmacological and clinical profile of mirtazapine.
CNS Drug Rev 2001;7(3):249-64 «PMID: 11607047»PubMed
- Arab A, Karimi E, Garaulet M, ym. Dietary patterns and insomnia symptoms: A systematic
review and meta-analysis. Sleep Med Rev 2024;75():101936 «PMID: 38714136»PubMed
- Arab A, Lempesis IG, Garaulet M, ym. Sleep and the Mediterranean diet: A systematic
review and meta-analysis. Sleep Med Rev 2025;80():102071 «PMID: 40081182»PubMed
- Arbon EL, Knurowska M, Dijk DJ. Randomised clinical trial of the effects of prolonged-release
melatonin, temazepam and zolpidem on slow-wave activity during sleep in healthy people.
J Psychopharmacol 2015;29(7):764-76 «PMID: 25922426»PubMed
- Arnold LM, Russell IJ, Diri EW, ym. A 14-week, randomized, double-blinded, placebo-controlled
monotherapy trial of pregabalin in patients with fibromyalgia. J Pain 2008;9(9):792-805
«PMID: 18524684»PubMed
- Auld F, Maschauer EL, Morrison I, ym. Evidence for the efficacy of melatonin in the
treatment of primary adult sleep disorders. Sleep Med Rev 2017;34():10-22 «PMID: 28648359»PubMed
- Baglioni C, Battagliese G, Feige B, ym. Insomnia as a predictor of depression: a meta-analytic
evaluation of longitudinal epidemiological studies. J Affect Disord 2011;135(1-3):10-9
«PMID: 21300408»PubMed
- Baglioni C, Bostanova Z, Bacaro V, ym. A Systematic Review and Network Meta-Analysis
of Randomized Controlled Trials Evaluating the Evidence Base of Melatonin, Light Exposure,
Exercise, and Complementary and Alternative Medicine for Patients with Insomnia Disorder.
J Clin Med 2020;9(6): «PMID: 32580450»PubMed
- Baglioni C, Bostanova Z, Bacaro V, ym. A Systematic Review and Network Meta-Analysis
of Randomized Controlled Trials Evaluating the Evidence Base of Melatonin, Light Exposure,
Exercise, and Complementary and Alternative Medicine for Patients with Insomnia Disorder.
J Clin Med 2020;9(6): «PMID: 32580450»PubMed
- Bai N, Cao J, Zhang H, ym. Digital cognitive behavioural therapy for patients with
insomnia and depression: A systematic review and meta-analysis. J Psychiatr Ment Health
Nurs 2024;31(4):654-667 «PMID: 38226714»PubMed
- Baker FC, de Zambotti M, Colrain IM, ym. Sleep problems during the menopausal transition:
prevalence, impact, and management challenges. Nat Sci Sleep 2018;10():73-95 «PMID: 29445307»PubMed
- Baker FC, Lampio L, Saaresranta T, ym. Sleep and Sleep Disorders in the Menopausal
Transition. Sleep Med Clin 2018;13(3):443-456 «PMID: 30098758»PubMed
- Bakker MH, Hugtenburg JG, Bet PM, ym. Effectiveness of low-dose amitriptyline and
mirtazapine in patients with insomnia disorder and sleep maintenance problems: a randomised,
double-blind, placebo-controlled trial in general practice (DREAMING). Br J Gen Pract
2025;75(756):e474-e483 «PMID: 39814428»PubMed
- Birkinshaw H, Friedrich CM, Cole P, ym. Antidepressants for pain management in adults
with chronic pain: a network meta-analysis. Cochrane Database Syst Rev 2023;5(5):CD014682
«PMID: 37160297»PubMed
- Bixler EO, Vgontzas AN, Lin HM, ym. Prevalence of sleep-disordered breathing in women:
effects of gender. Am J Respir Crit Care Med 2001;163(3 Pt 1):608-13 «PMID: 11254512»PubMed
- Blumer JL, Findling RL, Shih WJ, ym. Controlled clinical trial of zolpidem for the
treatment of insomnia associated with attention-deficit/ hyperactivity disorder in
children 6 to 17 years of age. Pediatrics 2009;123(5):e770-6 «PMID: 19403468»PubMed
- Bocca ML, Marie S, Lelong-Boulouard V, ym. Zolpidem and zopiclone impair similarly
monotonous driving performance after a single nighttime intake in aged subjects. Psychopharmacology
(Berl) 2011;214(3):699-706 «PMID: 21086117»PubMed
- Boullin P, Ellwood C, Ellis JG. Group vs. Individual Treatment for Acute Insomnia:
A Pilot Study Evaluating a "One-Shot" Treatment Strategy. Brain Sci 2016;7(1): «PMID: 28025539»PubMed
- Boyle J, Eriksson ME, Gribble L, ym. Randomized, placebo-controlled comparison of
amitriptyline, duloxetine, and pregabalin in patients with chronic diabetic peripheral
neuropathic pain: impact on pain, polysomnographic sleep, daytime functioning, and
quality of life. Diabetes Care 2012;35(12):2451-8 «PMID: 22991449»PubMed
- Braam W, Smits MG, Didden R, ym. Exogenous melatonin for sleep problems in individuals
with intellectual disability: a meta-analysis. Dev Med Child Neurol 2009;51(5):340-9
«PMID: 19379289»PubMed
- Brzezinski A, Vangel MG, Wurtman RJ, ym. Effects of exogenous melatonin on sleep:
a meta-analysis. Sleep Med Rev 2005;9(1):41-50 «PMID: 15649737»PubMed
- Budhiraja P, Budhiraja R, Goodwin JL, ym. Incidence of restless legs syndrome and
its correlates. J Clin Sleep Med 2012;8(2):119-24 «PMID: 22505854»PubMed
- Bulman A, D'Cunha NM, Marx W, ym. The effects of L-theanine consumption on sleep outcomes:
A systematic review and meta-analysis. Sleep Med Rev 2025;81():102076 «PMID: 40056718»PubMed
- Buscemi N, Vandermeer B, Hooton N, ym. Efficacy and safety of exogenous melatonin
for secondary sleep disorders and sleep disorders accompanying sleep restriction:
meta-analysis. BMJ 2006;332(7538):385-93 «PMID: 16473858»PubMed
- Buscemi N, Vandermeer B, Hooton N, ym. The efficacy and safety of exogenous melatonin
for primary sleep disorders. A meta-analysis. J Gen Intern Med 2005;20(12):1151-8
«PMID: 16423108»PubMed
- Carton L, Cottencin O, Lapeyre-Mestre M, ym. Off-Label Prescribing of Antipsychotics
in Adults, Children and Elderly Individuals: A Systematic Review of Recent Prescription
Trends. Curr Pharm Des 2015;21(23):3280-97 «PMID: 26088115»PubMed
- Chalet FX, Luyet PP, Rabasa C, ym. Daridorexant for patients with chronic insomnia
disorder: number needed to treat, number needed to harm, and likelihood to be helped
or harmed. Postgrad Med 2024;136(4):396-405 «PMID: 38814132»PubMed
- Chan V, Lo K. Efficacy of dietary supplements on improving sleep quality: a systematic
review and meta-analysis. Postgrad Med J 2022;98(1158):285-293 «PMID: 33441476»PubMed
- Cheung JMY, Jarrin DC, Ballot O, ym. A systematic review of cognitive behavioral therapy
for insomnia implemented in primary care and community settings. Sleep Med Rev 2019;44():23-36
«PMID: 30612061»PubMed
- Chiu HY, Lee HC, Liu JW, ym. Comparative efficacy and safety of hypnotics for insomnia
in older adults: a systematic review and network meta-analysis. Sleep 2021;44(5):
«PMID: 33249496»PubMed
- Corkum P, Lingley-Pottie P, Davidson F, ym. Better Nights/Better Days-Distance Intervention
for Insomnia in School-Aged Children With/Without ADHD: A Randomized Controlled Trial.
J Pediatr Psychol 2016;41(6):701-13 «PMID: 27189687»PubMed
- Cortesi F, Giannotti F, Sebastiani T, ym. Controlled-release melatonin, singly and
combined with cognitive behavioural therapy, for persistent insomnia in children with
autism spectrum disorders: a randomized placebo-controlled trial. J Sleep Res 2012;21(6):700-9
«PMID: 22616853»PubMed
- Costello RB, Lentino CV, Boyd CC, ym. The effectiveness of melatonin for promoting
healthy sleep: a rapid evidence assessment of the literature. Nutr J 2014;13():106
«PMID: 25380732»PubMed
- Davidson JR, Dickson C, Han H. Cognitive behavioural treatment for insomnia in primary
care: a systematic review of sleep outcomes. Br J Gen Pract 2019;69(686):e657-e664
«PMID: 31358494»PubMed
- De Crescenzo F, D'Alò GL, Ostinelli EG, ym. Comparative effects of pharmacological
interventions for the acute and long-term management of insomnia disorder in adults:
a systematic review and network meta-analysis. Lancet 2022;400(10347):170-184 «PMID: 35843245»PubMed
- de Mendonça FMR, de Mendonça GPRR, Souza LC, ym. Benzodiazepines and Sleep Architecture:
A Systematic Review. CNS Neurol Disord Drug Targets 2023;22(2):172-179 «PMID: 34145997»PubMed
- Doerr JP, Spiegelhalder K, Petzold F, ym. Impact of escitalopram on nocturnal sleep,
day-time sleepiness and performance compared to amitriptyline: a randomized, double-blind,
placebo-controlled study in healthy male subjects. Pharmacopsychiatry 2010;43(5):166-73
«PMID: 20603788»PubMed
- Dutta S, Singhal S, Shah R, ym. Daridorexant as a novel pharmacotherapeutic approach
in insomnia: a systematic review and meta-analysis. Expert Opin Drug Saf 2023;22(12):1237-1251
«PMID: 37526060»PubMed
- Edemann-Callesen H, Andersen HK, Ussing A, ym. Use of melatonin in children and adolescents
with idiopathic chronic insomnia: a systematic review, meta-analysis, and clinical
recommendation. EClinicalMedicine 2023;61():102048 «PMID: 37457117»PubMed
- Edinger JD, Arnedt JT, Bertisch SM, ym. Behavioral and psychological treatments for
chronic insomnia disorder in adults: an American Academy of Sleep Medicine clinical
practice guideline. J Clin Sleep Med 2021;17(2):255-262 «PMID: 33164742»PubMed
- El Rafihi-Ferreira R, Hasan R, Toscanini AC, ym. Acceptance and commitment therapy
versus cognitive behavioral therapy for insomnia: A randomized controlled trial. J
Consult Clin Psychol 2024;92(6):330-343 «PMID: 39023982»PubMed
- Ell J, Brückner HA, Johann AF, ym. Digital cognitive behavioural therapy for insomnia
reduces insomnia in nurses suffering from shift work disorder: A randomised-controlled
pilot trial. J Sleep Res 2024;33(6):e14193 «PMID: 38485134»PubMed
- Ell J, Schmid SR, Benz F, ym. Complementary and alternative treatments for insomnia
disorder: a systematic umbrella review. J Sleep Res 2023;32(6):e13979 «PMID: 37527850»PubMed
- Ellis JG, Cushing T, Germain A. Treating Acute Insomnia: A Randomized Controlled Trial
of a "Single-Shot" of Cognitive Behavioral Therapy for Insomnia. Sleep 2015;38(6):971-8
«PMID: 25515106»PubMed
- Evans ML, Pritts E, Vittinghoff E, ym. Management of postmenopausal hot flushes with
venlafaxine hydrochloride: a randomized, controlled trial. Obstet Gynecol 2005;105(1):161-6
«PMID: 15625158»PubMed
- Farag HM, Yunusa I, Goswami H, ym. Comparison of Amitriptyline and US Food and Drug
Administration-Approved Treatments for Fibromyalgia: A Systematic Review and Network
Meta-analysis. JAMA Netw Open 2022;5(5):e2212939 «PMID: 35587348»PubMed
- Farkas RH, Unger EF, Temple R. Zolpidem and driving impairment--identifying persons
at risk. N Engl J Med 2013;369(8):689-91 «PMID: 23923991»PubMed
- Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-analysis: melatonin for the treatment
of primary sleep disorders. PLoS One 2013;8(5):e63773 «PMID: 23691095»PubMed
- Ford DE, Kamerow DB. Epidemiologic study of sleep disturbances and psychiatric disorders.
An opportunity for prevention? JAMA 1989;262(11):1479-84 «PMID: 2769898»PubMed
- Freeman D, Waite F, Startup H, ym. Efficacy of cognitive behavioural therapy for sleep
improvement in patients with persistent delusions and hallucinations (BEST): a prospective,
assessor-blind, randomised controlled pilot trial. Lancet Psychiatry 2015;2(11):975-83
«PMID: 26363701»PubMed
- Furukawa Y, Nagaoka D, Sato S, ym. Cognitive behavioral therapy for insomnia to treat
major depressive disorder with comorbid insomnia: A systematic review and meta-analysis.
J Affect Disord 2024;367():359-366 «PMID: 39242039»PubMed
- Galgut Y, Hoyos C, Kempler L, ym. Cognitive and behavioural therapy for insomnia in
the treatment of adolescent insomnia: A systematic review and meta-analysis of randomised
controlled trials. J Sleep Res 2025;34(4):e14442 «PMID: 39680961»PubMed
- Gambacciani M, Ciaponi M, Cappagli B, ym. Effects of low-dose, continuous combined
hormone replacement therapy on sleep in symptomatic postmenopausal women. Maturitas
2005;50(2):91-7 «PMID: 15653005»PubMed
- Gambacciani M, Rosano G, Cappagli B, ym. Clinical and metabolic effects of drospirenone-estradiol
in menopausal women: a prospective study. Climacteric 2011;14(1):18-24 «PMID: 20979461»PubMed
- Glass J, Lanctôt KL, Herrmann N, ym. Sedative hypnotics in older people with insomnia:
meta-analysis of risks and benefits. BMJ 2005;331(7526):1169 «PMID: 16284208»PubMed
- Gray SL, Dublin S, Yu O, ym. Benzodiazepine use and risk of incident dementia or cognitive
decline: prospective population based study. BMJ 2016;352():i90 «PMID: 26837813»PubMed
- Guttuso T Jr, Kurlan R, McDermott MP, ym. Gabapentin's effects on hot flashes in postmenopausal
women: a randomized controlled trial. Obstet Gynecol 2003;101(2):337-45 «PMID: 12576259»PubMed
- Hachul H, Bittencourt LR, Andersen ML, ym. Effects of hormone therapy with estrogen
and/or progesterone on sleep pattern in postmenopausal women. Int J Gynaecol Obstet
2008;103(3):207-12 «PMID: 18812241»PubMed
- Handley AP, Williams M. The efficacy and tolerability of SSRI/SNRIs in the treatment
of vasomotor symptoms in menopausal women: a systematic review. J Am Assoc Nurse Pract
2015;27(1):54-61 «PMID: 24944075»PubMed
- Harris LM, Huang X, Linthicum KP, ym. Sleep disturbances as risk factors for suicidal
thoughts and behaviours: a meta-analysis of longitudinal studies. Sci Rep 2020;10(1):13888
«PMID: 32807889»PubMed
- Harvey AG, Soehner AM, Kaplan KA, ym. Treating insomnia improves mood state, sleep,
and functioning in bipolar disorder: a pilot randomized controlled trial. J Consult
Clin Psychol 2015;83(3):564-77 «PMID: 25622197»PubMed
- Hayashi M, Mishima K, Fukumizu M, ym. Melatonin Treatment and Adequate Sleep Hygiene
Interventions in Children with Autism Spectrum Disorder: A Randomized Controlled Trial.
J Autism Dev Disord 2022;52(6):2784-2793 «PMID: 34181143»PubMed
- Hays J, Ockene JK, Brunner RL, ym. Effects of estrogen plus progestin on health-related
quality of life. N Engl J Med 2003;348(19):1839-54 «PMID: 12642637»PubMed
- He D, Guo Z, Mcclure MA, ym. Cognitive-behavioral therapy for insomnia with objective
short sleep duration phenotype: A systematic review with meta-analysis. Sleep Med
Rev 2023;67():101736 «PMID: 36543054»PubMed
- Hertenstein E, Benz F, Schneider CL, ym. Insomnia-A risk factor for mental disorders.
J Sleep Res 2023;32(6):e13930 «PMID: 37211915»PubMed
- Hertenstein E, Feige B, Gmeiner T, ym. Insomnia as a predictor of mental disorders:
A systematic review and meta-analysis. Sleep Med Rev 2019;43():96-105 «PMID: 30537570»PubMed
- Hill Almeida LM, Flicker L, Hankey GJ, ym. Disrupted sleep and risk of depression
in later life: A prospective cohort study with extended follow up and a systematic
review and meta-analysis. J Affect Disord 2022;309():314-323 «PMID: 35490880»PubMed
- Ho FY, Chung KF, Yeung WF, ym. Self-help cognitive-behavioral therapy for insomnia:
a meta-analysis of randomized controlled trials. Sleep Med Rev 2015;19():17-28 «PMID: 25104471»PubMed
- Hoebert M, van der Heijden KB, van Geijlswijk IM, ym. Long-term follow-up of melatonin
treatment in children with ADHD and chronic sleep onset insomnia. J Pineal Res 2009;47(1):1-7
«PMID: 19486273»PubMed
- Holbrook AM, Crowther R, Lotter A, ym. Meta-analysis of benzodiazepine use in the
treatment of insomnia. CMAJ 2000;162(2):225-33 «PMID: 10674059»PubMed
- Huang K, Li S, He R, ym. Efficacy of cognitive behavioral therapy for insomnia (CBT-I)
in older adults with insomnia: A systematic review and meta-analysis. Australas Psychiatry
2022;30(5):592-597 «PMID: 35968818»PubMed
- Häuser W, Bernardy K, Uçeyler N, ym. Treatment of fibromyalgia syndrome with antidepressants:
a meta-analysis. JAMA 2009;301(2):198-209 «PMID: 19141768»PubMed
- Häuser W, Bernardy K, Uçeyler N, ym. Treatment of fibromyalgia syndrome with gabapentin
and pregabalin--a meta-analysis of randomized controlled trials. Pain 2009;145(1-2):69-81
«PMID: 19539427»PubMed
- Illeez OG, Oktay KNK, Aktas I, ym. Comparison of the effects of duloxetine and pregabalin
on pain and associated factors in patients with knee osteoarthritis. Rev Assoc Med
Bras (1992) 2022;68(3):377-383 «PMID: 35442367»PubMed
- Imfeld P, Bodmer M, Jick SS, ym. Benzodiazepine Use and Risk of Developing Alzheimer's
Disease or Vascular Dementia: A Case-Control Analysis. Drug Saf 2015;38(10):909-19
«PMID: 26123874»PubMed
- Islam MM, Iqbal U, Walther B, ym. Benzodiazepine Use and Risk of Dementia in the Elderly
Population: A Systematic Review and Meta-Analysis. Neuroepidemiology 2016;47(3-4):181-191
«PMID: 28013304»PubMed
- Jiang L, Xiong Y, Cui J. Comparison of the Efficacy and Safety of Duloxetine and Gabapentin
in Diabetic Peripheral Neuropathic Pain: A Meta-Analysis. Contrast Media Mol Imaging
2022;2022():4084420 «PMID: 35299589»PubMed
- Karsten J, Hagenauw LA, Kamphuis J, ym. Low doses of mirtazapine or quetiapine for
transient insomnia: A randomised, double-blind, cross-over, placebo-controlled trial.
J Psychopharmacol 2017;31(3):327-337 «PMID: 28093029»PubMed
- Kravitz HM, Zhao X, Bromberger JT, ym. Sleep disturbance during the menopausal transition
in a multi-ethnic community sample of women. Sleep 2008;31(7):979-90 «PMID: 18652093»PubMed
- Kriikku P, Ojanperä I. Fatal concentrations of antidepressant and antipsychotic drugs
in postmortem femoral blood. J Anal Toxicol 2023;47(7):615-622 «PMID: 37440364»PubMed
- Krystal AD, Lankford A, Durrence HH, ym. Efficacy and safety of doxepin 3 and 6 mg
in a 35-day sleep laboratory trial in adults with chronic primary insomnia. Sleep
2011;34(10):1433-42 «PMID: 21966075»PubMed
- Kunz D, Dauvilliers Y, Benes H, ym. Long-Term Safety and Tolerability of Daridorexant
in Patients with Insomnia Disorder. CNS Drugs 2023;37(1):93-106 «PMID: 36484969»PubMed
- Lappalainen P, Langrial S, Oinas-Kukkonen H ym. ACT for sleep – Internet-delivered
self-help ACT for sub-clinical and clinical insomnia: A randomized controlled trial.
J Contextual Behav Sci 2019;12:119-127
- Lavigne JE, Hur K, Gibbons JB, ym. Associations between insomnia medications and risk
of death by suicide. Sleep Med 2023;111():199-206 «PMID: 37801864»PubMed
- Leppik IE, Roth-Schechter GB, Gray GW ym. Double-blind, placebo- controlled comparison
of zolpidem, triazolam, and temazepam in elderly patients with insomnia. Drug development
research 1997;403:230-8
- Leufkens TR, Lund JS, Vermeeren A. Highway driving performance and cognitive functioning
the morning after bedtime and middle-of-the-night use of gaboxadol, zopiclone and
zolpidem. J Sleep Res 2009;18(4):387-96 «PMID: 19552733»PubMed
- Li L, Wu C, Gan Y, ym. Insomnia and the risk of depression: a meta-analysis of prospective
cohort studies. BMC Psychiatry 2016;16(1):375 «PMID: 27816065»PubMed
- Liira J, Verbeek JH, Costa G, ym. Pharmacological interventions for sleepiness and
sleep disturbances caused by shift work. Cochrane Database Syst Rev 2014;2014(8):CD009776
«PMID: 25113164»PubMed
- Lin W, Li N, Yang L, ym. The efficacy of digital cognitive behavioral therapy for
insomnia and depression: a systematic review and meta-analysis of randomized controlled
trials. PeerJ 2023;11():e16137 «PMID: 37927792»PubMed
- Liu RT, Steele SJ, Hamilton JL, ym. Sleep and suicide: A systematic review and meta-analysis
of longitudinal studies. Clin Psychol Rev 2020;81():101895 «PMID: 32801085»PubMed
- Loprinzi CL, Kugler JW, Sloan JA, ym. Venlafaxine in management of hot flashes in
survivors of breast cancer: a randomised controlled trial. Lancet 2000;356(9247):2059-63
«PMID: 11145492»PubMed
- Loprinzi CL, Sloan JA, Perez EA, ym. Phase III evaluation of fluoxetine for treatment
of hot flashes. J Clin Oncol 2002;20(6):1578-83 «PMID: 11896107»PubMed
- Louzada LL, Machado FV, Quintas JL, ym. The efficacy and safety of zolpidem and zopiclone
to treat insomnia in Alzheimer's disease: a randomized, triple-blind, placebo-controlled
trial. Neuropsychopharmacology 2022;47(2):570-579 «PMID: 34635802»PubMed
- Ma ZR, Shi LJ, Deng MH. Efficacy of cognitive behavioral therapy in children and adolescents
with insomnia: a systematic review and meta-analysis. Braz J Med Biol Res 2018;51(6):e7070
«PMID: 29791593»PubMed
- Maki PM, Panay N, Simon JA. Sleep disturbance associated with the menopause. Menopause
2024;31(8):724-733 «PMID: 38916279»PubMed
- Malow BA, Findling RL, Schroder CM, ym. Sleep, Growth, and Puberty After 2 Years of
Prolonged-Release Melatonin in Children With Autism Spectrum Disorder. J Am Acad Child
Adolesc Psychiatry 2021;60(2):252-261.e3 «PMID: 31982581»PubMed
- Mansikkamäki K, Raitanen J, Nygård CH, ym. Sleep quality and aerobic training among
menopausal women--a randomized controlled trial. Maturitas 2012;72(4):339-45 «PMID: 22673453»PubMed
- Maruani J, Reynaud E, Chambe J, ym. Efficacy of melatonin and ramelteon for the acute
and long-term management of insomnia disorder in adults: A systematic review and meta-analysis.
J Sleep Res 2023;32(6):e13939 «PMID: 37434463»PubMed
- Marupuru S, Arku D, Campbell AM, ym. Use of Melatonin and/on Ramelteon for the Treatment
of Insomnia in Older Adults: A Systematic Review and Meta-Analysis. J Clin Med 2022;11(17):
«PMID: 36079069»PubMed
- McCleery J, Sharpley AL. Pharmacotherapies for sleep disturbances in dementia. Cochrane
Database Syst Rev 2020;11(11):CD009178 «PMID: 33189083»PubMed
- Meeuwsen IB, Samson MM, Duursma SA, ym. The influence of tibolone on quality of life
in postmenopausal women. Maturitas 2002;41(1):35-43 «PMID: 11809341»PubMed
- Mehri M, Chehrzad MM, Mardani A, ym. The effect of behavioral parent training on sleep
problems of school-age children with ADHD: A parallel randomized controlled trial.
Arch Psychiatr Nurs 2020;34(4):261-267 «PMID: 32828358»PubMed
- Mei Z, Cai C, Luo S, ym. The efficacy of cognitive behavioral therapy for insomnia
in adolescents: a systematic review and meta-analysis of randomized controlled trials.
Front Public Health 2024;12():1413694 «PMID: 39628800»PubMed
- Miller BJ, McCall WV. Meta-analysis of insomnia, suicide, and psychopathology in schizophrenia.
Curr Opin Psychiatry 2023;36(3):156-165 «PMID: 36762664»PubMed
- Montgomery P, Stores G, Wiggs L. The relative efficacy of two brief treatments for
sleep problems in young learning disabled (mentally retarded) children: a randomised
controlled trial. Arch Dis Child 2004;89(2):125-30 «PMID: 14736626»PubMed
- Morin CM, Vallières A, Guay B, ym. Cognitive behavioral therapy, singly and combined
with medication, for persistent insomnia: a randomized controlled trial. JAMA 2009;301(19):2005-15
«PMID: 19454639»PubMed
- Musiek ES, Holtzman DM. Mechanisms linking circadian clocks, sleep, and neurodegeneration.
Science 2016;354(6315):1004-1008 «PMID: 27885006»PubMed
- Nadeem IM, Shanmugaraj A, Sakha S, ym. Energy Drinks and Their Adverse Health Effects:
A Systematic Review and Meta-analysis. Sports Health 2021;13(3):265-277 «PMID: 33211984»PubMed
- Nelson HD, Vesco KK, Haney E, ym. Nonhormonal therapies for menopausal hot flashes:
systematic review and meta-analysis. JAMA 2006;295(17):2057-71 «PMID: 16670414»PubMed
- Nguyen PV, Dang-Vu TT, Forest G, ym. Mirtazapine for chronic insomnia in older adults:
a randomised double-blind placebo-controlled trial-the MIRAGE study. Age Ageing 2025;54(3):
«PMID: 40135470»PubMed
- NIH State-of-the-Science Conference Statement on manifestations and management of
chronic insomnia in adults. NIH Consens State Sci Statements 2005;22:1-30
- Ong JC, Crawford MR, Dawson SC, ym. A randomized controlled trial of CBT-I and PAP
for obstructive sleep apnea and comorbid insomnia: main outcomes from the MATRICS
study. Sleep 2020;43(9): «PMID: 32170307»PubMed
- Osler M, Jørgensen MB. Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics
With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort
and Nested Case-Control Study. Am J Psychiatry 2020;177(6):497-505 «PMID: 32252539»PubMed
- Osler M, Rosenqvist TW, Wium-Andersen IK, ym. Sedative drug prescription patterns
in Danish adults from 2002 through 2021. A register-based cohort study. J Psychiatr
Res 2024;172():129-135 «PMID: 38377668»PubMed
- Pan B, Ge L, Lai H, ym. The Comparative Effectiveness and Safety of Insomnia Drugs:
A Systematic Review and Network Meta-Analysis of 153 Randomized Trials. Drugs 2023;83(7):587-619
«PMID: 36947394»PubMed
- Pandya KJ, Morrow GR, Roscoe JA, ym. Gabapentin for hot flashes in 420 women with
breast cancer: a randomised double-blind placebo-controlled trial. Lancet 2005;366(9488):818-24
«PMID: 16139656»PubMed
- Papadopoulos N, Sciberras E, Hiscock H, ym. The Efficacy of a Brief Behavioral Sleep
Intervention in School-Aged Children With ADHD and Comorbid Autism Spectrum Disorder.
J Atten Disord 2019;23(4):341-350 «PMID: 25646022»PubMed
- Partinen M, Hirvonen K, Hublin C, ym. Effects of after-midnight intake of zolpidem
and temazepam on driving ability in women with non-organic insomnia. Sleep Med 2003;4(6):553-61
«PMID: 14607350»PubMed
- Pentinlehto J. Off-label prescribing of antipsychotics - a questionnaire survey of
Finnish physicians. Psychiatria Fennica 2021; 52:22-48
- Pigeon WR, Pinquart M, Conner K. Meta-analysis of sleep disturbance and suicidal thoughts
and behaviors. J Clin Psychiatry 2012;73(9):e1160-7 «PMID: 23059158»PubMed
- Polo-Kantola P, Erkkola R, Helenius H, ym. When does estrogen replacement therapy
improve sleep quality? Am J Obstet Gynecol 1998;178(5):1002-9 «PMID: 9609575»PubMed
- Polo-Kantola P, Rauhala E, Erkkola R, ym. Estrogen replacement therapy and nocturnal
periodic limb movements: a randomized controlled trial. Obstet Gynecol 2001;97(4):548-54
«PMID: 11275026»PubMed
- Pourmotabbed A, Awlqadr FH, Mehrabani S, ym. Ultra-Processed Food Intake and Risk
of Insomnia: A Systematic Review and Meta-Analysis. Nutrients 2024;16(21): «PMID: 39519600»PubMed
- Pressman MR. Sleep driving: sleepwalking variant or misuse of z-drugs? Sleep Med Rev
2011;15(5):285-92 «PMID: 21367628»PubMed
- Prowting J, Maresh S, Vaughan S, ym. Mirtazapine reduces susceptibility to hypocapnic
central sleep apnea in males with sleep-disordered breathing: a pilot study. J Appl
Physiol (1985) 2021;131(1):414-423 «PMID: 34080920»PubMed
- Reynolds AC, Sweetman A, Crowther ME, ym. Is cognitive behavioral therapy for insomnia
(CBTi) efficacious for treating insomnia symptoms in shift workers? A systematic review
and meta-analysis. Sleep Med Rev 2023;67():101716 «PMID: 36459948»PubMed
- Richelson E. Interactions of antidepressants with neurotransmitter transporters and
receptors and their clinical relevance. J Clin Psychiatry 2003;64 Suppl 13():5-12
«PMID: 14552650»PubMed
- Richelson E. Pharmacology of antidepressants. Mayo Clin Proc 2001;76(5):511-27 «PMID: 11357798»PubMed
- Riedel A, Benz F, Deibert P, ym. The effect of physical exercise interventions on
insomnia: A systematic review and meta-analysis. Sleep Med Rev 2024;76():101948 «PMID: 38749363»PubMed
- Riemann D, Dressle RJ, Spiegelhalder K. Insomnia Guidelines – The European Update
2023. Clinical and Translational Neuroscience 2024; 8(1):10
- Ritterband LM, Shaffer KM, Thorndike FP, ym. A randomized controlled trial of a digital
cognitive behavioral therapy for insomnia for older adults. NPJ Digit Med 2025;8(1):458
«PMID: 40681664»PubMed
- Rosenberg R, Murphy P, Zammit G, ym. Comparison of Lemborexant With Placebo and Zolpidem
Tartrate Extended Release for the Treatment of Older Adults With Insomnia Disorder:
A Phase 3 Randomized Clinical Trial. JAMA Netw Open 2019;2(12):e1918254 «PMID: 31880796»PubMed
- Rossignol DA, Frye RE. Melatonin in autism spectrum disorders: a systematic review
and meta-analysis. Dev Med Child Neurol 2011;53(9):783-792 «PMID: 21518346»PubMed
- Roth T, Lankford DA, Bhadra P, ym. Effect of pregabalin on sleep in patients with
fibromyalgia and sleep maintenance disturbance: a randomized, placebo-controlled,
2-way crossover polysomnography study. Arthritis Care Res (Hoboken) 2012;64(4):597-606
«PMID: 22232085»PubMed
- Roth T, Rogowski R, Hull S, ym. Efficacy and safety of doxepin 1 mg, 3 mg, and 6 mg
in adults with primary insomnia. Sleep 2007;30(11):1555-61 «PMID: 18041488»PubMed
- Salazar-Méndez J, Viscay-Sanhueza N, Pinto-Vera C, ym. Cognitive behavioral therapy
for insomnia in people with chronic musculoskeletal pain. A systematic review and
dose-response meta-analysis. Sleep Med 2024;122():20-26 «PMID: 39111059»PubMed
- Samara MT, Huhn M, Chiocchia V, ym. Efficacy, acceptability, and tolerability of all
available treatments for insomnia in the elderly: a systematic review and network
meta-analysis. Acta Psychiatr Scand 2020;142(1):6-17 «PMID: 32521042»PubMed
- Sangal RB, Blumer JL, Lankford DA, ym. Eszopiclone for insomnia associated with attention-deficit/hyperactivity
disorder. Pediatrics 2014;134(4):e1095-103 «PMID: 25266438»PubMed
- Santi D, Debbi V, Costantino F, ym. Microbiota Composition and Probiotics Supplementations
on Sleep Quality-A Systematic Review and Meta-Analysis. Clocks Sleep 2023;5(4):770-792
«PMID: 38131749»PubMed
- Scharf M, Rogowski R, Hull S, ym. Efficacy and safety of doxepin 1 mg, 3 mg, and 6
mg in elderly patients with primary insomnia: a randomized, double-blind, placebo-controlled
crossover study. J Clin Psychiatry 2008;69(10):1557-64 «PMID: 19192438»PubMed
- Schwerdtle B, Kübler A, Schlarb A. External Validity of the Multicomponent Group Treatment
KiSS for School-Aged Children With Insomnia. Behav Sleep Med 2020;18(2):147-162 «PMID: 30482055»PubMed
- Sciberras E, Mulraney M, Mensah F, ym. Sustained impact of a sleep intervention and
moderators of treatment outcome for children with ADHD: a randomised controlled trial.
Psychol Med 2020;50(2):210-219 «PMID: 30654852»PubMed
- Scott J, Kallestad H, Vedaa O, ym. Sleep disturbances and first onset of major mental
disorders in adolescence and early adulthood: A systematic review and meta-analysis.
Sleep Med Rev 2021;57():101429 «PMID: 33549912»PubMed
- Shahar E, Redline S, Young T, ym. Hormone replacement therapy and sleep-disordered
breathing. Am J Respir Crit Care Med 2003;167(9):1186-92 «PMID: 12531779»PubMed
- Shahdadian F, Boozari B, Saneei P. Association between short sleep duration and intake
of sugar and sugar-sweetened beverages: A systematic review and meta-analysis of observational
studies. Sleep Health 2023;9(2):159-176 «PMID: 36424247»PubMed
- Shash D, Kurth T, Bertrand M, ym. Benzodiazepine, psychotropic medication, and dementia:
A population-based cohort study. Alzheimers Dement 2016;12(5):604-13 «PMID: 26602630»PubMed
- Sheaves B, Freeman D, Isham L, ym. Stabilising sleep for patients admitted at acute
crisis to a psychiatric hospital (OWLS): an assessor-blind pilot randomised controlled
trial. Psychol Med 2018;48(10):1694-1704 «PMID: 29108526»PubMed
- Shin JW, Kim S, Shin YJ, ym. Comparison of Acceptance and Commitment Therapy (ACT)
and Cognitive Behavior Therapy (CBT) for Chronic Insomnia: A Pilot Randomized Controlled
Trial. Nat Sci Sleep 2023;15():523-531 «PMID: 37431325»PubMed
- Silva VPO ym. Effect of Physical Exercise on Sleep Quality in Elderly Adults: A Systematic
Review with a Meta-Analysis of Controlled and Randomized Studies.Journal of Ageing
and Longevity2022;2(2):85-97
- Simon L, Steinmetz L, Feige B, ym. Comparative efficacy of onsite, digital, and other
settings for cognitive behavioral therapy for insomnia: a systematic review and network
meta-analysis. Sci Rep 2023;13(1):1929 «PMID: 36732610»PubMed
- Sivertsen B, Omvik S, Pallesen S, ym. Cognitive behavioral therapy vs zopiclone for
treatment of chronic primary insomnia in older adults: a randomized controlled trial.
JAMA 2006;295(24):2851-8 «PMID: 16804151»PubMed
- Stearns V, Beebe KL, Iyengar M, ym. Paroxetine controlled release in the treatment
of menopausal hot flashes: a randomized controlled trial. JAMA 2003;289(21):2827-34
«PMID: 12783913»PubMed
- Stearns V, Slack R, Greep N, ym. Paroxetine is an effective treatment for hot flashes:
results from a prospective randomized clinical trial. J Clin Oncol 2005;23(28):6919-30
«PMID: 16192581»PubMed
- Stuttard L, Beresford B, Clarke S, ym. A preliminary investigation into the effectiveness
of a group-delivered sleep management intervention for parents of children with intellectual
disabilities. J Intellect Disabil 2015;19(4):342-55 «PMID: 25792540»PubMed
- Suvanto-Luukkonen E, Koivunen R, Sundström H, ym. Citalopram and fluoxetine in the
treatment of postmenopausal symptoms: a prospective, randomized, 9-month, placebo-controlled,
double-blind study. Menopause 2005;12(1):18-26 «PMID: 15668596»PubMed
- Sweetman A, Lack L, Catcheside PG, ym. Cognitive and behavioral therapy for insomnia
increases the use of continuous positive airway pressure therapy in obstructive sleep
apnea participants with comorbid insomnia: a randomized clinical trial. Sleep 2019;42(12):
«PMID: 31403168»PubMed
- Sweetman A, Lack L, McEvoy RD, ym. Effect of depression, anxiety, and stress symptoms
on response to cognitive behavioral therapy for insomnia in patients with comorbid
insomnia and sleep apnea: a randomized controlled trial. J Clin Sleep Med 2021;17(3):545-554
«PMID: 33118927»PubMed
- Sweetman A, McEvoy RD, Smith S, ym. The effect of cognitive and behavioral therapy
for insomnia on week-to-week changes in sleepiness and sleep parameters in patients
with comorbid insomnia and sleep apnea: a randomized controlled trial. Sleep 2020;43(7):
«PMID: 31927569»PubMed
- Tassniyom K, Paholpak S, Tassniyom S, ym. Quetiapine for primary insomnia: a double
blind, randomized controlled trial. J Med Assoc Thai 2010;93(6):729-34 «PMID: 20572379»PubMed
- Tian C, Wei Y, Xu M, ym. The effects of exercise on insomnia disorders: An umbrella
review and network meta-analysis. Sleep Med 2024;115():66-75 «PMID: 38335829»PubMed
- Toulis KA, Tzellos T, Kouvelas D, ym. Gabapentin for the treatment of hot flashes
in women with natural or tamoxifen-induced menopause: a systematic review and meta-analysis.
Clin Ther 2009;31(2):221-35 «PMID: 19302896»PubMed
- Tu AY, Crawford MR, Dawson SC, ym. A randomized controlled trial of cognitive behavioral
therapy for insomnia and PAP for obstructive sleep apnea and comorbid insomnia: effects
on nocturnal sleep and daytime performance. J Clin Sleep Med 2022;18(3):789-800 «PMID: 34648425»PubMed
- Turner AD, Ong JC, Jones AL, ym. Neurocognitive functioning in comorbid insomnia and
sleep apnea patients is better after positive airway pressure therapy, but worse after
cognitive behavioral therapy for insomnia: exploratory analysis of cognitive outcomes
from the Multidisciplinary Approach to the Treatment of Insomnia and Comorbid Sleep
Apnea study. Sleep 2023;46(8): «PMID: 37148183»PubMed
- Tworoger SS, Yasui Y, Vitiello MV, ym. Effects of a yearlong moderate-intensity exercise
and a stretching intervention on sleep quality in postmenopausal women. Sleep 2003;26(7):830-6
«PMID: 14655916»PubMed
- Uchimura N, Ozone M, Suzuki M, ym. Long-term safety and efficacy of daridorexant in
Japanese patients with insomnia disorder. Sleep Med 2024;122():64-70 «PMID: 39128336»PubMed
- Valladales-Restrepo LF, Sánchez-Ramírez N, Ospina-Sánchez S, ym. Pharmacological Management
of Acute and Chronic Insomnia: A Cross-Sectional Study. Clin Neuropharmacol 2024;47(6):207-212
«PMID: 39297769»PubMed
- Vallières A, Morin CM, Guay B, ym. Sequential treatment for chronic insomnia: a pilot
study. Behav Sleep Med 2004;2(2):94-112 «PMID: 15600227»PubMed
- Van der Heijden KB, Smits MG, Van Someren EJ, ym. Effect of melatonin on sleep, behavior,
and cognition in ADHD and chronic sleep-onset insomnia. J Am Acad Child Adolesc Psychiatry
2007;46(2):233-41 «PMID: 17242627»PubMed
- van der Zweerde T, Bisdounis L, Kyle SD, ym. Cognitive behavioral therapy for insomnia:
A meta-analysis of long-term effects in controlled studies. Sleep Med Rev 2019;48():101208
«PMID: 31491656»PubMed
- van Straten A, van der Zweerde T, Kleiboer A, ym. Cognitive and behavioral therapies
in the treatment of insomnia: A meta-analysis. Sleep Med Rev 2018;38():3-16 «PMID: 28392168»PubMed
- Vermeeren A, Riedel WJ, van Boxtel MP, ym. Differential residual effects of zaleplon
and zopiclone on actual driving: a comparison with a low dose of alcohol. Sleep 2002;25(2):224-31
«PMID: 11905433»PubMed
- Verster JC, Veldhuijzen DS, Volkerts ER. Residual effects of sleep medication on driving
ability. Sleep Med Rev 2004;8(4):309-25 «PMID: 15233958»PubMed
- Vgontzas AN, Fernandez-Mendoza J, Liao D, ym. Insomnia with objective short sleep
duration: the most biologically severe phenotype of the disorder. Sleep Med Rev 2013;17(4):241-54
«PMID: 23419741»PubMed
- Walsh JK, Soubrane C, Roth T. Efficacy and safety of zolpidem extended release in
elderly primary insomnia patients. Am J Geriatr Psychiatry 2008;16(1):44-57 «PMID: 18165461»PubMed
- Wang L, Pan Y, Ye C, ym. A network meta-analysis of the long- and short-term efficacy
of sleep medicines in adults and older adults. Neurosci Biobehav Rev 2021;131():489-496
«PMID: 34560134»PubMed
- Weiss MD, Wasdell MB, Bomben MM, ym. Sleep hygiene and melatonin treatment for children
and adolescents with ADHD and initial insomnia. J Am Acad Child Adolesc Psychiatry
2006;45(5):512-519 «PMID: 16670647»PubMed
- Welton AJ, Vickers MR, Kim J, ym. Health related quality of life after combined hormone
replacement therapy: randomised controlled trial. BMJ 2008;337():a1190 «PMID: 18719013»PubMed
- Wiegand MH, Landry F, Brückner T, ym. Quetiapine in primary insomnia: a pilot study.
Psychopharmacology (Berl) 2008;196(2):337-8 «PMID: 17922110»PubMed
- Xie L, Kang H, Xu Q, ym. Sleep drives metabolite clearance from the adult brain. Science
2013;342(6156):373-7 «PMID: 24136970»PubMed
- Xie Y, Liu S, Chen XJ, ym. Effects of Exercise on Sleep Quality and Insomnia in Adults:
A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front Psychiatry
2021;12():664499 «PMID: 34163383»PubMed
- Xu D, Cardell E, Broadley SA, ym. Efficacy of Face-to-Face Delivered Cognitive Behavioral
Therapy in Improving Health Status of Patients With Insomnia: A Meta-Analysis. Front
Psychiatry 2021;12():798453 «PMID: 35002813»PubMed
- Xu H, Zhang C, Qian Y, ym. Efficacy of melatonin for sleep disturbance in middle-aged
primary insomnia: a double-blind, randomised clinical trial. Sleep Med 2020;76():113-119
«PMID: 33157425»PubMed
- Yang L, Zhang J, Luo X, ym. Effectiveness of one-week internet-delivered cognitive
behavioral therapy for insomnia to prevent progression from acute to chronic insomnia:
A two-arm, multi-center, randomized controlled trial. Psychiatry Res 2023;321():115066
«PMID: 36716552»PubMed
- Yue JL, Chang XW, Zheng JW, ym. Efficacy and tolerability of pharmacological treatments
for insomnia in adults: A systematic review and network meta-analysis. Sleep Med Rev
2023;68():101746 «PMID: 36701954»PubMed
- Zhang MM, Ma Y, Du LT, ym. Sleep disorders and non-sleep circadian disorders predict
depression: A systematic review and meta-analysis of longitudinal studies. Neurosci
Biobehav Rev 2022;134():104532 «PMID: 35041878»PubMed
- Zhang X, Xu H, Zhang Z, ym. Efficacy and Safety of Pregabalin for Fibromyalgia in
a Population of Chinese Subjects. J Pain Res 2021;14():537-548 «PMID: 33658841»PubMed
- Zhong G, Wang Y, Zhang Y, ym. Association between Benzodiazepine Use and Dementia:
A Meta-Analysis. PLoS One 2015;10(5):e0127836 «PMID: 26016483»PubMed
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