Takaisin Tulosta

Grading the quality of evidence

Info
Editors
6.6.2011
Code Quality of evidence Definition
A High We are very confident that the true effect lies close to that of the estimate of the effect.
  • Several high-quality studies with consistent results
  • In special cases: one large, high-quality multi-centre trial
B Moderate We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
  • One high-quality study
  • Several studies with some limitations
C Low Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect.
  • One or more studies with severe limitations
D Very low We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect.
  • Expert opinion
  • No direct research evidence
  • One or more studies with very severe limitations

Source: GRADE (Grading of Recommendations Assessment, Development and Evaluation) Working Group «http://www.gradeworkinggroup.org»1 (modified by the EBM Guidelines Editorial Team)