Takaisin Tulosta

Three- or four-drug versus two-drug antiretroviral maintenance regimens for HIV infection

Evidence summaries
20.3.2003
Editors

Level of evidence: A

Combination of three or four antiviral drugs results in reduced rate of virologic failure.

A Cochrane review «Three‐ or four‐ versus two‐drug antiretroviral maintenance regimens for HIV infection»1 «Rutherford GW, Sangani PR, Kennedy GE. Three- or four- versus two-drug antiretroviral maintenance regimens for HIV infection. Cochrane Database Syst Rev 2003;(4):CD002037. »1 included 4 trials. Maintenance therapies involving fewer than three drugs were associated with higher risk of virologic failure (OR 5.55, 95% CI 3.14 to 9.80).

References

  1. Rutherford GW, Sangani PR, Kennedy GE. Three- or four- versus two-drug antiretroviral maintenance regimens for HIV infection. Cochrane Database Syst Rev 2003;(4):CD002037. «PMID: 14583945»PubMed