Age, disc hemorrhages (for normal tension glaucoma), baseline visual field loss, baseline intraocular pressure, and exfoliation syndrome seem to be associated with glaucomatous visual field progression.
Evidence-Based Review
To examine which prognostic factors are associated with glaucomatous visual field progression, by consulting relevant databases, 2733 articles were published up to September 2010, of which 85 articles investigating prognostic factors for visual field progression in patients with open-angle glaucoma (OAG) were eligible. Results for each factor in tables, noting the direction of the association between the prognostic factor and progression, and the accompanying P value. Four authors, working blind to the factors, independently judged the extent to which a prognostic factor was associated with glaucomatous visual field progression. If there were different associations for normal-tension glaucoma (NTG) studies, they were judged separately. Consensus was reached during group meetings.
A total of 103 different prognostic factors were investigated in 85 articles. The following factors were clearly associated with glaucomatous visual field progression: age, disc hemorrhages (for NTG), baseline visual field loss, baseline intraocular pressure (IOP), and exfoliation syndrome. An association was unlikely for family history of glaucoma, atherosclerosis, systemic hypertension, visual acuity, sex (for NTG), systolic blood pressure, myopic refractive error (for NTG), and Raynaud's phenomenon «Ernest PJ, Schouten JS, Beckers HJ ym. An evidence...»1.